Project List

We search and we search, and then we research.

Welcome to Dr. Pearce’s Researchtorium

Our current research interests are centered around a knowledge of how to measure volume using complex admittance.

Catheter-based complex admittance measurement can be transformed into a signal representing blood pool volume in real time. Our group has refined this technique to work even very small animals like mice.

The current state of the art in CHF detection only tests positive when the patient has edema (NYHA stage III or higher CHF). By measuring the change in volume over time, we are developing a much earlier detection model.

Validation of our procedure of volume measurement comes from MRI studies which we perform in mice. Imaging mice is inherently challenging because of their very small size.

This project involves miniaturization of the present discrete instrumentation so that real - time measurements can be made on ambulatory animals.

This project involves the measurement of the electrical admittance of ischemic cardiac tissue in animals in vivo to detect measurable changes in complex tissue electrical properties as a result of ischemia.

Real-Time Pressure Volume Analysis

Telemetric Circuitry Development

MRI Validation in Mice

Early Detection of Congestive Heart Failure (CHF)

Ischemia Detection

Project List